The artist has given the full amount of his £25,000 award cash to the trust for venues, which operates to protect the UK's small music venues.
The star was awarded the award on 16 October as his latest record the album was declared the best record of the last 12 months.
He has chosen to donate the funds to the MVT, in acknowledgment of the vital role small stages had in his early career.
"I personally wouldn't be doing this success if it weren't for all the shows I did around the region, and beyond, when I was just getting going," said Sam Fender. "These spaces are renowned, but they are in difficulty."
Beginning in 2023, at least 150 of these venues have ceased operations – about one-sixth of the total UK scene.
Over the past year, well-known musicians such as Pulp, Coldplay, Katy Perry and Ed Sheeran have all supported the MVT in its attempts to help venues survive, by adding a minor surcharge to their ticket costs, which goes to help independent venues.
He also joined in, generating more than £100,000 on his recent tour to help numerous local spots across the UK.
The donation supported spaces that were dealing with imminent closure due to issues arising from water damage, fire incidents and personal losses, as well as regulatory hurdles, legal disputes and noise complaints.
Other venues obtained monetary aid in modernizing amenities and technical equipment that positively impacted artists and audiences.
"The idea that funds from performances in large arenas supports the independent spots, where it begins for performers like me, is just common sense," Sam Fender has commented.
Fender is far from the only musician to donate his honor funds to good deeds.
When they received the prize in 1996 for their album Different Class, lead singer Cocker announced that the act would donate their prize money to the charity War Child.
In 2002, rapper and singer she split her bounty across several good causes, such as the children's charity and a charity for Sickle Cell.
"Additionally, I donated a thousand pounds to Highgate Newtown, to their gymnastics class, because I trained in gymnastics when I was a child and they required better apparatus," Ms Dynamite told a publication.
Two years ago, the band gave their winnings to the youth organization that developed their band, in addition to other independent music bodies.
And winners that year M People gave their award to a MS organization after a friend was diagnosed the condition.
"Winning was sufficient," stated singer Small. "The cash was the cherry on top but we didn't need the extra, because we had the honor. So our success touched somebody else's life."
In the past week, the trust announced it had rescued two small stages in south-east England, by transferring them to local control.
One venue in Southampton and The Croft in the city were bought under the public acquisition initiative, which is backed by Arts Council England and supporters who buy "shares" in the buildings.
